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CaseReport Article

Severe Complication to Phytomenadione after Intramuscular Injection in Woman in Labor: Case Report and Review of Literature

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Pages 381-382 | Received 02 Sep 1988, Accepted 20 Jan 1989, Published online: 03 Aug 2009
 

Abstract

A 28-year-old woman in labor developed a severe anaphylactoid reaction, necessitating acute cesarean section, with subsequent neonatal death, after receiving 10 mg of phytomenadione (Konakion®) by the intramuscular route. Allergologic investigations revealed no type I reaction against the drug, and the symptoms were considered to be caused by drug-induced intolerance. Prophylactic administration of phytomenadione to the infant rather than to the parturient is recommended.

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