Restorative treatment strategies for patients with cleidocranial dysplasia

Abstract

Objective. To develop a suitable treatment strategy for patients with cleidocranial dysplasia (CCD) who miss the optimal early treatment stage. Materials and methods. This study enrolled 15 patients with CCD who had all missed the optimal treatment stage and were diagnosed with CCD through clinical examinations and genetic tests. Based on the chief complaints and requirements of the patients, three different therapeutic schedules were devised for these patients. Schedules I (periodontal and endodontic treatments) and II (periodontal, endodontic and prosthodontic treatments) were used for patients with low requirements, whereas Schedule III (multidisciplinary strategy, including periodontal, endodontic, surgical, orthodontic and prosthodontic treatments) was used for patients with high requirements. Results. Schedules I, II and III were used in five, seven and three patients, respectively. Schedule III treatments produced the best outcomes in terms of occlusion and esthetics. Conclusions. Schedule III based on a comprehensive multidisciplinary therapy is an ideal restorative therapeutic strategy and can achieve good outcomes for patients with CCD who missed the optimal treatment stage.

Key Words:

• cleidocranial dysplasia
• multidisciplinary treatment
• RUNX2
• supernumerary teeth

Acknowledgments

We thank the patients and their families for their co-operation and enthusiastic support.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.