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Acta Odontologica Scandinavica Volume 29, 1971 - Issue 5
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Original Article

Characterization of Collagen Biosynthesis in Rabbit Dental Pulp In Vitro

Veli-Jukka Uitto Departments of Medical Chemistry and Pharmacology, University of Helsinki, Finland
&
Risto Antila Departments of Medical Chemistry and Pharmacology, University of Helsinki, Finland
Pages 609-617 | Received 06 May 1971, Published online: 02 Jul 2009
 
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Abstract

Collagen biosynthesis in the dental pulp was studied by measuring the rate of 14C-hydroxyproline formation in vitro and assaying the activity of protocollagen proline hydroxylase (PPH). The maximal formation of 14C-hydroxyproline from 14C-proline in an incubation medium occurred between the pH values 7.4 and 8.2. No significant differences in the rate of collagen biosynthesis could be demonstrated between the molar and incisor pulps. The methods of the present study seem to be useful for further investigation on collagen metabolism in the dental pulp.

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Related Research Data

The Extracellular Matrix of the Dental Pulp and Dentin
Source: SAGE Publications

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