Release of fluoride and metal ions from root surfaces after topical application of TiF₄, SnF₂, and NaF in vitro

Abstract

Aqueous solutions of TiF₄ cause a rapid uptake and a long-lasting retention of fluoride when applied to dentin. The aim of this study was therefore to investigate the pattern of fluoride release after TiF₄ application in vitro, compared with SnF₂ and NaF application. TiF₄. SnF₂, and NaF were applied for 4 min and 1 min to standardized areas of six groups of root surface specimens immersed in distilled water. Untreated specimens were used as controls. The water was changed daily for 30 days, and F concentrations measured by an ion-selective electrode. All test groups showed a rapid decline in F concentration. In the 4-min group F concentration more than double the detection limit of the F electrode could be registered the first 28 days for TiF₄, 11 days for SnF₂, and 7 days for NaF. In the 1-min group periods of F registration were shorter. Analysis of Sn by atomic absorption spectrophotometry showed decreasing concentrations in the first 12-day samples in the 1-min and 4-min groups. Traces of Ti were found in the first few samples, but no pattern of release could be observed.

Key Words:

• Cariostutic agents
• dentin
• F electrode
• in vitro study
• preventive dentistry