Ultrastructure of Laryngeal Precanceroses

Abstract

The authors have described the ultrastructure of the pachydermia papilloma and the hyperplastic form of chronic laryngitis. These alterations result in the change of cell contact; pathological keratinization phenomena according to the behaviour of the nucleus and the cytoplasmic organelles can be regarded as precancerous changes. The continuance of the basal membrane breaks at certain points even in the precancerous alteration, and the protuberances of the cytoplasm of the basal cells break through the epithelial-connective tissue border. Viruses could not be found in the papilloma.