Vesicles and Basement Membrane Changes Associated with Hydrops of the Saccule and Endolymphatic duct and Sac

Abstract

The significance of vesiculations of the membranous labyrinth are discussed from the point of view of normal and increased pinocytosis activity. Basement membrane changes in the membranous wall of the saccule are demonstrated in a patient with hydrops of the saccule and endolymphatic duct and sac. The vesiculations and basement membrane changes are believed to indicate the movement of large amounts of fluid across the membrane walls.