Oestriol Succinate: Its Effect on the Haemorrhage in Adenotonsillectomy and Tonsillectomy

Abstract

In order to assess the haemostatic effect of oestrogens, the amount of haemorrhage in adenotonsillectomy and tonsillectomy was measured and the number of postoperative haemorrhages analysed in two groups of patients. One group received Oestriol Succinate, while the other group received a placebo. The total average haemorrhage was in the same range of magnitude in both groups. In the group treated with Oestriol Succinate there was a smaller number of postoperative haemorrhages that did not require treatment (clots), and the adenotonsillectomized patients had less operative haemorrhage in relation to a corresponding number of the untreated patients. This appears to indicate an effect of the substance on capillary bleedings.