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Original Article

A Study of Experimental Deafness in Human Volunteers with a New Oral Antidiabetic Drug R. 94

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Pages 537-542 | Received 01 Aug 1967, Published online: 08 Jul 2009
 

Abstract

a) R 94 (N. Benzine Sulphonyl-N-Isopropyl Urea) a new synthetic Anti Diabetic drug when used in the treatment of Diabetis caused a reversible deafness affecting the higher frequencies. b) This deafness increases with the continuation of the intake of the drug, and is relieved on removal of the drug or the administration of a vasodilator drug, e.g. Nicotinic Acid in a daily dosage of 200 mg. c) A study of the drug R 94 on 26 human volunteers is presented.

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