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Original Article

Effect of Endolymphatic SAC Ablation in the Rabbit and Cat

Pages 333-346 | Received 16 Jan 1968, Published online: 08 Jul 2009
 

Abstract

Tests of cochlear and vestibular function were carried out on two species of animals (6 cats and 15 rabbits) following which the left endolymphatic sac was removed in some with the remaining being control animals. Subsequent tests of function revealed depression of cochlear microphonics in both species with marked loss of vestibular function in the rabbit while remaining normal in the cat. Histologic study revealed there was mild cochlear hydrops in the cats and severe cochlear and vestibular hydrops in the rabbit which correlated to the loss of function noted. It therefore followed that the endolymphatic sac ablation was responsible for the hydrops in both species and was most prominent in the rabbit in this short term experiment.

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