Granular Cell Myoblastoma of the Larynx

Abstract

Five cases of granular cell myoblastoma of the larynx have been reported. One occurred in a boy of 12 years; another, in a female of 36 years, recurred after 14 years. The histology has been described and in 3 cases the interstitial “angular body” cells of Bangle were demonstrated. The histochemical findings were considered to be in general accord with those of previously reported investigations. Theories of aetiology and pathogenesis have been briefly reviewed. Sixty-four cases of granular cell myoblastoma of the larynx were found in the literature, no details being available in four of these. The total number of recorded cases (69) represents more than 10% of “myoblastomas” in all sites. The peak age incidence of the laryngeal cases was in the fourth decade with a male predominance of nearly 2:1.