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Abstract
The author has studied chronologically with the electron microscope the cellular alterations that follow the penetration of the pollen (Betula alba) into a sensitized mucosa. The study has been done between one hour and twenty seven days. A precise sequence of different cell “waves” going from the eosinophil to the plasmocyte is described and as a conclusion a theory of the immunological autonomy of the nasal mucosa is proposed.