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Abstract
Quantitative analysis of acid mucopoly-saccharides in the kanamyciri intoxicated guinea pig cochlea was performed using the modified turbidi-metric method based on the formation of insoluble complexes between acid mucopolysaccharides and cetyltrimethylammonium bromide, in combination with enzymic analysis. A decreased quantity of acid mucopolysaccharides in the ha vascularis and the spiral ligament was observed in comparison with the normal. The factors involved in the decrease of acid mucopolysaccharides and its effect on the inner ear function were discussed.