Homotransplantation Of Canine Trachea After Denervation Of The Spleen: A Preliminary Report

I. Toivio Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

U. Siirala Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

Sirkka Lauerma Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

S. Rapo Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

Th. Tallberg Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

K. Mahlberg Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

J. Tapaninen Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

H. Meurala Otolaryngological Hospital, University of Helsinki, Helsinki, Finland

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Abstract

The rejection phenomenon has been the major obstacle to advances in organ transplantation, and immunodepression has been only partially effective in controlling rejection. The role of the spleen in the rejection of transplanted tissues is still but poorly understood. We have performed trachea transplantations which are based upon an observation that the rejection phenomenon can be altered through denervation of the spleen. The results of these experiments will be discussed.

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Homotransplantation Of Canine Trachea After Denervation Of The Spleen: A Preliminary Report

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Homotransplantation Of Canine Trachea After Denervation Of The Spleen: A Preliminary Report

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