Analysis Of Bone Remodelling In The Otosclerotic Stapes By Means Of Tetracycline Labelling

M. Roberto Departments of Bioacoustics and of Histology, Embryology of the University of Bari, Italy; Department of Otolaryngology, University of Milan, Italy; Department of Otolaryngology, Hospital “La Fe”, Valencia, Spain

J. Garcia-Ibañez Departments of Bioacoustics and of Histology, Embryology of the University of Bari, Italy; Department of Otolaryngology, University of Milan, Italy; Department of Otolaryngology, Hospital “La Fe”, Valencia, Spain

E. Bocca Departments of Bioacoustics and of Histology, Embryology of the University of Bari, Italy; Department of Otolaryngology, University of Milan, Italy; Department of Otolaryngology, Hospital “La Fe”, Valencia, Spain

S. Iurato Departments of Bioacoustics and of Histology, Embryology of the University of Bari, Italy; Department of Otolaryngology, University of Milan, Italy; Department of Otolaryngology, Hospital “La Fe”, Valencia, Spain

Abstract

The distribution and the amount of bone tissue formed in the otosclerotic focus during 6 days were studied in 16 otosclerotic and 3 normal stapedes, by means of tetracycline labelling. The relative amount of fluorescent new-formed bone was expressed as a percentage ratio NB/(NB + PB) of new bone (NB) on the pre-existing bone (PB). In the more active foci a layer of new-formed bone was noticed around nearly all the vascular cavities. In the less active and quiescent foci the new-formed bone was only noticed on the edge of some osteons. In the normal stapedes no trace of new-formed bone was observed.

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Analysis Of Bone Remodelling In The Otosclerotic Stapes By Means Of Tetracycline Labelling

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Analysis Of Bone Remodelling In The Otosclerotic Stapes By Means Of Tetracycline Labelling

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