Abstract
Mediastinoscopy was made in 338 patients with lung cancer and biopsies were taken from paratracheal, parabronchial and carinal lymph ncdes. Positive biopsies were obtained in 159 cases (47%). In 168 right lung tumors, metastases were found ip-silaterally in 49% and contralaterally in 20%. Of 170 left lung tumors, 45% showed metastases ip-silaterally and 25% also on the contralateral side. Contralateral metastases from the right upper lobe were rare (2%). Histologically, epidermoid carcincma showed the lowest number of metastases (34%) while the microcellular anaplastic type had metastases in 81%. When the mediastinal lymph nodes become involved, curative surgery is very rarely useful and radio- or chemotherapy should be considered.