Occurrence and Distribution of Vip Nerves in the Nasal Mucosa and Tracheobronchial Wall

R. Uddman The Department of Otolaryngology, University Hospital, Malmö; Departments of Histology and Pharmacology, University of Lund, Lund, Sweden

J. Alumets The Department of Otolaryngology, University Hospital, Malmö; Departments of Histology and Pharmacology, University of Lund, Lund, Sweden

O. Densert The Department of Otolaryngology, University Hospital, Malmö; Departments of Histology and Pharmacology, University of Lund, Lund, Sweden

R. Hakanson The Department of Otolaryngology, University Hospital, Malmö; Departments of Histology and Pharmacology, University of Lund, Lund, Sweden

F. Sundler The Department of Otolaryngology, University Hospital, Malmö; Departments of Histology and Pharmacology, University of Lund, Lund, Sweden

Abstract

Nerves displaying vasoactive intestinal peptide (VIP) immunoreactivity were detected in the upper respiratory tract of guinea pigs, rabbits and cats. VIP nerves were numerous in the cat, less numerous in the rabbit and rare in the guinea pig. In the nasal mucosa, fine varicose VIP nerves were found to surround nasal glands and small blood vessels. In the tracheobronchial wall VIP nerves were observed around seromucous glands, blood vessels and smooth muscle. Ganglia located in the walls of the trachea and main bronchi contained clusters of VIP im-munoreactive nerve cell bodies, conceivably representing the origin of the VIP fibres found in this region.

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Occurrence and Distribution of Vip Nerves in the Nasal Mucosa and Tracheobronchial Wall

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Occurrence and Distribution of Vip Nerves in the Nasal Mucosa and Tracheobronchial Wall

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