Determination of Cellmediated Immunity Against Tumour Associated Antigens in Patients of Ent

R. Nowak Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

M. Günther Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

H. L. Jenssen Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

M. Seyfarth Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

H. Werner Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

H. P. Putzke Aus der Hals-Nasen-Ohrenklinik, der Urologischen Klinik, der Forschungsabteilung Immunologie und dem Pathologischen Institut des Bereiches Medizin der Wilhelm-Pieck-Universität, Rostock, DDR

Abstract

In an unconventional assay system (MEM Test) Caspary & Field claimed in 1971 to have detected lymphocyte sensitization to a common tumour antigen in all patients with cancer. There was no evidence of histogenetic specificity to the reaction and their conclusions are in direct contradiction to those of all workers who have studied the cytotoxic activity of lymphocytes on tumour cells. To improve the specificity of the test system, another type of tumour antigen was used in MEM Test incubation. Tumour-associated antigens were prepared according to the hypertonic salt extraction method introduced by Reisfeld, Leonard, Meltzer et al. As shown by the results, information could be gained concerning the existence of a malignant tumour and its location.

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Determination of Cellmediated Immunity Against Tumour Associated Antigens in Patients of Ent

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Determination of Cellmediated Immunity Against Tumour Associated Antigens in Patients of Ent

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