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Original Article

Ultrastructural Study of the Human Spiral Ganglion

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Pages 53-62 | Received 04 Apr 1979, Published online: 08 Jul 2009
 

Abstract

Electron microscopic study of the human spiral ganglion was conducted on 17 ears from 12 individuals aged 9 months to 92 years. Two types of neurons, large and small, with distinct cytological characteristics were found. Both types of neurons were myelinated and unmyelinated; however, a majority of the population was unmyelinated (94%). The distribution of myelinated neurons varied greatly among individuals, though a slight increase in their population was noted in aged individuals, the highest count being 28% in a specimen from an individual 75 years old. The small neurons constituted 6% of the population, and their cytoplasms were highly filamentous in both myelinated and unmyelinated types. The findings of this study provide no evidence as to the functional significance of the myelination of spiral ganglion cells.

Zusammenfassung

Elektronenmikroskopische Untersuchungen des menschlichen Ganglion spirale wurden in 17 Ohren von 12 Individuen im Alter von 9 Monaten bis zu 92 Jahren durchgeführt. Zwei Arten von Neuronen, und zwar groβe und kleine mit bestimmten cytologischen Merkmalen wurden gefunden. Beide Arten waren sowohl myelinisiert als auch unmyelinisiert. Die Mehrzahl war unmyelinisiert (94%). Der Anteil myelinisierter Neurone variierte stark von Individuum zu Individuum, doch eine Zunahme bei alten Personen wurde gefunden. Der gröβte Anteil war 28% bei einer Person im Alter von 75 Jahren. Sechs Prozent etwa waren kleine Neurone. Ihr Cytoplasma enthielt viele Neurofilamente sowohl in der myelinisierten als auch in der unmyelinisierten Art. Die vorliegende Untersuchung sagt nichts betreffend die funktionelle Bedeutung der Mye-linisierung von Spiralganglionzellen aus.

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