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Original Article

The Origin of Vasoactive Intestinal Polypeptide (VIP) Nerves in the Feline Nasal Mucosa

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Pages 152-156 | Received 04 Apr 1979, Published online: 08 Jul 2009
 

Abstract

The feline nasal mucosa is richly supplied with vasoactive intestinal polypeptide (VIP) immunoreactive nerve fibres. The nerves occur in the subepithelial connective tissue, around small blood vessels and around the acini of seromucous glands. The pterygopalatine ganglion contains numerous VIP immunoreactive nerve cell bodies among non-reactive ones. Extirpation of the ganglion results in an almost complete disappearance of VlP-containing nerves in the nasal mucosa, while sectioning of the preganglionic nerve (Vidian nerve) does not affect the number of nasal VIP nerves. Hence the bulk of VIP nerve fibers in the nasal mucosa derive from cell bodies located in the pterygopalatine ganglion.

Zusammenfassung

Durch immunohistochemische Studien der Nasenschleimhaut bei der Katze konnte ein reiches Vorkommen von Nervenfibern nachgewiesen werden, die gegen vasoaktive intestinale Polypeptide (VIP) immunoreaktiv sind. Die Nerven kamen im subepithelien Bindegewebe vor und umgaben kleine Blutgefäβe und seromuköse Drüsen. In dem Ganglion pterygopalatinum wurden zahlreiche VIP immunoreaktive Nervenkörper beobachtet. Die Exstirpation des Ganglions resultierte in einer ausgesprochenen Reduktion der VIP-enthaltenden Nerven in der Nasen-schleimhaut. Die Unterteilung des praganglionischen Nerven (N. Vidianus) hatte jedoch keinen Einfluβ auf die An-zahl von VIP Nerven. Somit stammt die Mehrzahl der VIP Nerven in der Nasenschleimhaut von Nervenkörpern aus dem pterygopalatinen Ganglion.

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