Effects of Vasoactive Intestinal Polypeptide on Resistance and Capacitance Vessels in the Nasal Mucosa

L. Malm Department of Otolaryngology, University Hospital, Malmö; Department of Histology, University of Lund, Lund, Sweden

F. Sundler Department of Otolaryngology, University Hospital, Malmö; Department of Histology, University of Lund, Lund, Sweden

R. Uddman Department of Otolaryngology, University Hospital, Malmö; Department of Histology, University of Lund, Lund, Sweden

Abstract

Vasoactive intestinal polypeptide (VIP) im-munoreactive nerves have previously been demonstrated in the feline nasal mucosa. In the present investigation it isshown that VIP given close arterially dilates both resistance and capacitance vessels in the nose of the cat. This vasodilatation is atropine resistant. It is suggested that VIP serves a physiological role in the neurogenic control of blood vessels in the nasal mucosa.

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Effects of Vasoactive Intestinal Polypeptide on Resistance and Capacitance Vessels in the Nasal Mucosa

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Effects of Vasoactive Intestinal Polypeptide on Resistance and Capacitance Vessels in the Nasal Mucosa

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