Convergence of Central and Peripheral Signals on Vestibular Cells

Abstract

Nerve and cortical input convergence patterns, representing the fore- and hindlimb, were studied in single cells located in the lateral vestibular nucleus of the cat. Deitersian cells responded with excitation to cortical stimulation with a latency ranging from 4 to 14 msec, while responses ranged from 9 to 12 msec to radial nerve stimulation and from 14 to 18 msec to sciatic nerve stimulation. Lateral vestibular nuclear neurons responding to radial nerve stimulation also receive the main cortical input from the sensorimotor cortical area concerned with the fore-limb. Neurons responding to sciatic nerve stimulation receive an equal cortical input from both fore- and hind-limb areas of the sensorimotor cortex. In a few cells different combinations of convergence of cortical and peripheral inputs were also observed.