Metaplasic Bone Tissue in Tympanosclerosis

Abstract

Two different tissues have been observed in specimens of tympanosclerotic material studied under light and electron microscopy. The first. devoid of cells and blood vessels, is a dense fibrous tissue similar to that already described in fibrous tympanosclerosis. The sec ond resembles a bone tissue, containing osteocytes and vascular channels: it is laid down by metaplasic fibro-blasts following the invasion of the first tissue by osteo-clasts and blood vessels after its calcification.