Abstract
Conclusions: The mCI surgical technique led to reduced impedance and minimized disturbance of the microenvironment inside the cochlea. Atraumatic surgical techniques and inflammation-reduction strategies may preserve the cochlear architecture and prevent fibrotic development. Objectives: To assess the advantages of a modified minimal access technique in cochlear implantation as well as to investigate the effects of intra-operative application of inflammation reduction strategies on the intra-cochlear impedance. Methods: One hundred patients received a 31.5 mm long Med-El standard electrode array fully inserted into the cochlea and did not have surgical complications post-operation. Patients were divided into two groups according to the surgical technique that was used for implantation: 50 were in the modified minimal access cochlear implant (mCI) surgery group and 50 were in the traditional CI surgery group. Intra-cochlear impedance values were measured at initial activation (4 weeks post-operatively). Electrode impedance values were compared between the surgery groups. Results: Electrode impedance values were significantly lower in the mCI group than in the CI surgery group at initial activation (5.01 kOhm vs 6.10 kOhm, respectively, F = 13.761, p = 0.000). The differences between the two groups were most prominent for the electrodes located at the basal region of the cochlea.
Funding information
This work was supported by grants from the Project of the National Natural Science Foundation of China (Grant Nos. 81230020, 81371096), a grant from the Minister of Science and Technology of China (2012BAI09B02), grants from the National Basic Research Program of China (973 Program) (2014CB541706, 2014CB541701).