Abstract
The time courses of hearing recovery resulting from two types of treatment of sudden deafness patients, defibrinogenation (DF) therapy and betamethazone (BM) therapy, were analyzed and compared. a paired double-blind comparative study was performed on 168 patients. the average hearing level was 79.2 dBHL in the DF therapy group (n=82) and 82.3 dBHL in the BM therapy group (n=86). the DF group showed significantly better hearing 1 week after start of treatment at frequencies of 0.25,0.5 and 1 kHz. After 2 weeks of treatment, the average hearing level for the frequency range of 0.25-4 kHz was 47.0 dBHL with DF therapy and 55.8 dBHL with BM therapy. Thus, the DF group still showed better hearing than the BM group (p< 0.10, t-test), but not as significantly as after 1 week. It is concluded that therapy for increasing blood circulation is important in the early phase of sudden deafness, especially for hearing loss in the low to middle frequency range.