Furosemide vor Test for the Detection of Endolymphatic Hydrops

Muneharu Ito Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Yukio Watanabe Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Hideo Shojaku Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Hideto Kobayashi Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Shin Aso Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Kanemasa Mizukoshi Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan

Abstract

In order to detect endolymphatic hydrops, we applied three neurootologic examination methods, including the furosemide VOR test, the glycerol dehydration test, and electrocochleography in 61 patients with unilateral Meniere's disease, 21 patients with delayed endolymphatic hydrops, and 10 patients with syphilitic labyrinthitis. The positive rate of the furosemide VOR test in patients with endolymphatic hydrops was more than 50%. Inconsistencies were observed between the results of the furosemide VOR test, the glycerol test and/or electrocochleography. Therefore, combined test battery of these tests is useful clinically for detecting endolymphatic hydrops in the vestibular and cochlear systems.

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Furosemide vor Test for the Detection of Endolymphatic Hydrops

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