Observation of Apical Part and Nerve Terminals of Human Vestibular Hair Cells

Abstract

The human vestibular sensory epithelia of macula utriculi in 3 cases of acoustic neurinoma were examined by conventional and intermediate voltage electron microscopes. The apical part and the nerve terminals of hair cells were studied by means of a computer-aided three-dimensional (3-D) reconstruction technique. The sensory epithelia were fairly well preserved. Most type I and all type II hair cells appeared as those described in the other reports. However, some type I hair cells were incompletely surrounded by nerve calyces and received direct contacts from the efferent nerve endings. These type I hair cells were also innervated by a few neighbouring afferent nerve calyces. The stereocilia and the cuticular plate of type I hair cells differed from those of type II hair cells. The mean diameter of type I hair cell stereocilia was 488 ± 59 nm and that of type II hair cells was 373 ± 21 nm. The cuticular plate of type I hair cells resembled a cone and was about several times as thick as that of type II hair cells which was similar to a flat disc.

Key Words:

• cuticular plate
• efferent nerve ending
• innervating pattern
• stereocilia
• type I and type II hair cells