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Acta Oto-Laryngologica Volume 116, 1996 - Issue 3
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Original Article

Localization of the Mineralocorticoid Receptor in Rat Cochlear Tissue

Xiaofei Yao Departments of Anatomy & Cell Biology, University of Florida, Gainesville, FL, 32610, USA
&
Kyle E. Rarey Departments of Anatomy & Cell Biology, University of Florida, Gainesville, FL, 32610, USA; Departments of Otolaryngology, University of Florida, Gainesville, FL, 32610, USA
Pages 493-496 | Received 04 Apr 1995, Accepted 30 Jun 1995, Published online: 08 Jul 2009
 
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Abstract

Distribution of the mineralocorticoid receptor within rat cochlear tissue was studied by immunohistochemistry. Intense immunoreactions of mineralocorticoid receptor antibodies were observed in outer and inner hair cells of the organ of Corti, stria vascularis, spiral ligament and spiral ganglion cells. Moderate to weak immunostaining was observed in the spiral limbus and cochlear nerve. Results of this study suggest that cochlear tissue is a mineralocorticoid hormone target tissue.

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