![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Kakoi H, Anniko M. Auditory epithelial migration. II: Morphological evidence for auditory epidermal cell migration in rat.
Morphology, of the tympanic membrane (TM) and external auditory canal (EAC) was studied in healthy, intact rat ears, TM-perforated ears (3 days after making the perforation) and TM-perforation-healed ears (14, 28 and 42 days after making the perforation). in intact ears, the epidermis in the annular region of the EAC displayed a characteristic appearance with cytoplasmic protrusions. We termed these protrusions as “finger-like projections”. in contrast to the rat, the annular region of the EAC in the guinea-pig did not show “finger-like projections”. Following a perforation in the centre of the anterior or the posterior quadrant of the pars tensa in rats the “finger-like projections” disappeared from the annular region on the perforated side of the EAC, while the projections remained on the malleus side of the perforation edge. in perforation-healed ears analysed 42 days after the perforation, the “finger-like projections” had recurred in the annular region on the perforated side of the EAC. the “finger-like projections” are likely to express maturation (keratinization) and desquamation of epidermal cells in the pars tensa and also could constitute morphological evidence of their migration on the TM.