Abstract
Thirty three chronic psychiatric hospital subjects with oral tardive dyskinesia were divided into three groups. The subjects were matched for severity of symptoms then randomly assigned to treatment with a placebo, 1g deanol or 2g deanol per day.
Statistical analysis showed that after 30 days treatment, there was a significant reduction in the mean rating of the movements of the group of 11 subjects on 2g deanol per day. Six of these subjects showed substantial reduction in movement. Further studies using this dosage of deanol are warranted.