Abstract
Objective: To highlight the complications of nitrous oxide abuse.
Clinical picture: A case is presented of a myeloneuropathy in a 21-year-old woman who had been abusing nitrous oxide, obtained from whipped cream bulbs, who was referred to a psychiatric hospital with a diagnosis of conversion disorder. Nitrous oxide toxicity has been reported in medical and dental professions and a few cases of myeloneuropathy due to induced vitamin B12 deficiency have been reported. This would appear to be the first reported case of myeloneuropathy resulting from nitrous oxide abuse from whipped cream propellants as a recreational drug in the community.
Treatment: Three doses of intramuscular hydroxy cobalamin (1000 μg) over the course of 1 week.
Outcome: Her neurological symptoms and anxiety settled.
Conclusions: Nitrous oxide is becoming more popular as a recreational drug; its complications should be noted and a thorough neurological examination performed if abuse is suspected.