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Abstract
The depressant action of CO2 on various spinal reflexes has been emphasized by many authors. The present study concerns the effects of respiratory acidosis on various types of lumbar dorsal root potentials (DRP).
Inhalation of a gas mixture containing 10–20% CO2 is followed by: (a) a constant increase in the amplitude of DRPs of segmental and cortical origin; (b) variable changes (most frequently diminution) in the amplitude of heterosegmental DRPs.
The magnitude of the changes induced by a given concentration of inhaled C02 varies greatly from one preparation to another.
Various mechanisms are discussed which may explain the increase in the DRP during respiratory acidosis.