![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
The changes in levels of 5-hydroxytryptamine (5-HT), 5-hydroxyindoleacetic acid (5-HIAA), norepinephrine (NE), 3-methoxy-4-hydroxyphenylethyleneglycol sulphate (MHPG-SO4) and dopamine (DA) of rat brain were studied after electric acupuncture stimulation (EAS).
We found that the mean values of cerebral 5-HT and 5-HIAA after EAS were increased 16% (p<0.001) and 24% (p<0.01) respectively, significantly higher than those of controls, whereas the mean value of cerebral NE was decreased 14% (p<0.01), significantly lower than that of the controls. The cerebral MHPG-SO4 and DA in both groups showed no significant difference.
In a second series of experiments with another group of rats, EAS was administered once a day for ten days. There was no statistical significance between the treated group and the control group in the differences in brain contents of all three monoamine neurotransmitters and 5-HIAA.