Occurrences of Electroencephalographic (EEG) Patterns that Resemble Epileptiform Discharges in Background EEG in Epileptic Patients

Abstract

The relationships of background EEG to epileptiform discharge development were studied in 9 epileptic patients having generalized spike and wave complexes (SWCs) with a maximum at the frontal location on either side. The instantaneous power spectrum of EEGs at F3, F4, C3, C4, P3, P4, O1, O2, T3 and T4 was estimated with wavelet transform. Subsequently, the similarity of power spectra between SWCs and background EEG was determined by use of Kullback-Leibler information and artificial neural network in each patient. Both similarity measures revealed that EEG patterns similar to SWCs occurred in the background activity just before SWCs at frontal locations. These findings suggested that these SWC-like EEG events occurred as poorly developed epileptiform discharges buried in the background activity.

Key Words:

• Electroencephalogram
• epilepsy
• spike and wave complexes
• wavelet analysis
• artificial neural network
• Kullback-Leibler information