The Effect of Aneurin on Uterine Contractions

Abstract

1. The effect of aneurin on inadequate pains in 47 cases has been studied. An injection of 100 mg was administered and the results were recorded tocographically.

2. In cases of inertia no clear effect could be observed.

3. In cases of exhaustion the strength of uterine contractions was increased as a rule, sometimes to such an extent that there was a therapeutical value of the procedure.

4. The effect is ascribed by the writers to the circumstance that aneurin promotes the acetylization of choline, thus rendering the synaptic reaction more sensitive. It is suggested that the phenomenon is largely due to hypervitaminosis produced by large doses of vitamin Bi.