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Abstract
Albumin metabolism was studied in 19 normally pregnant women and 11 healthy, non-pregnant women.
In pregnancy plasma volume was significantly higher, serum albumin concentration significantly lower than in controls. The intravascular mass of albumin was normal.
The fractional catabolic rate and the rate of synthesis were not different from those of controls. A hormonal inhibition of synthesis is motivated.
Distribution ratio was significantly higher in pregnant women; the extravascular mass of albumin was reduced.