Automated Blood Galactose Analysis as a Screening Method for Galactosaemia in Milk-Fed Newborns

Abstract

The method of using automated analysis of galactose with galactose oxidase in blood absorbed on discs of filter paper is proposed. A galactose concentrations of 33–100 mg/100 ml the recovery was about 80 per cent the day, 60 per cent after 2 weeks storage at room temperature, and nearly 100 per cent after storage at −80° C for various lengths of time. Blood samples from 202 healthy infants five days old gave zero values for galactose. As yet, no infant with hereditary galactosaemia has been investigated.

Key Words:

• Galactose
• galactosaemia
• galactose oxidase
• screening test