The Hepatic Metabolism of Ethanol in Patients with Cirrhosis of the Liver

K. Winkler Third Medical Department and Department of Clinical Physiology, Kommunehospitalet, Rigshospitalet, Copenhagen; Department of Biochemistry A, University of Copenhagen, Rigshospitalet, Copenhagen; Medical Department B, Bispebjerg Hospital, Department A, Hepatology, Rigshospitalet, Copenhagen

F. Lundquist Third Medical Department and Department of Clinical Physiology, Kommunehospitalet, Rigshospitalet, Copenhagen; Department of Biochemistry A, University of Copenhagen, Rigshospitalet, Copenhagen; Medical Department B, Bispebjerg Hospital, Department A, Hepatology, Rigshospitalet, Copenhagen

N. Tygstrup Third Medical Department and Department of Clinical Physiology, Kommunehospitalet, Rigshospitalet, Copenhagen; Department of Biochemistry A, University of Copenhagen, Rigshospitalet, Copenhagen; Medical Department B, Bispebjerg Hospital, Department A, Hepatology, Rigshospitalet, Copenhagen

Abstract

Splanchnic ethanol uptake was lower in cirrhosis compared to normals. The accelerating effect of fructose on ethanol metabolism was smaller in cirrhosis. From studies of portocaval shunts, it appeared that acetate, formed from ethanol, was not metabolized in the liver. The peripheral metabolism of acetate, glucose and lactate was diminished in cirrhosis.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

The Hepatic Metabolism of Ethanol in Patients with Cirrhosis of the Liver

Information for

Open access

Opportunities

Help and information

The Hepatic Metabolism of Ethanol in Patients with Cirrhosis of the Liver

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature