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Original Article

Determination of Diamine Oxidase Activity in Normal Human Blood Serum

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Pages 163-168 | Received 08 Apr 1969, Accepted 04 Jun 1969, Published online: 08 Jul 2009
 

Abstract

The method with 14C-putrescine as the substrate for routine measurement of serum (plasma) diamine oxidase (histaminase) during pregnancy, and mola hydatidosa (chorionepitelioma) has been modified. The optimal experimental conditions for determination of diamine oxidase (DAO) activity in normal human blood serum are given. Normal range for serum DAO is 0 to 20 mU/1. The majority, however, grouped around 4 mU/1, i.e., about 1/500 of the serum DAO activity in the last trimester of normal pregnancy.

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