Evaluation of Two Methods for Measuring δ- Aminolaevulinic Acid in Urine

Abstract

The concentration of δ-aminolaevulinic acid in the urine is known to be a good measure of the degree of intoxication with lead. The first methods for quantitative determination of the acid were laborious but have since been simplified. One of these modifications, the one described by Grabecki et al. was compared with the technique originally elaborated by Mauzerall & Granick. It was found that the former procedure was as reliable as the latter, and both quicker and cheaper. The modification by Grabecki et al. is therefore recommended in the control of lead workers.

Key Words:

• δ-aminolaevulinic acid
• lead intoxication