Renal Excretion of ⁵¹Cr-EDTA Studied with Stop Flow Technique

Abstract

The renal clearance of ⁵¹Cr-EDTA in dogs was found to be about 10 per cent lower than inulin clearance. To test whether this difference is caused by tubular reabsorption, stop flow experiments were performed during various types of diuresis. No evidence was found for tubular reabsorption of ⁵¹Cr-EDTA. The discrepancy is probably caused by decomposition of the complex during storage.

Key Words:

• Chromium isotopes
• EDTA
• glomerular filtration rate
• inulin
• kidney
• kidney function tests
• kidney tubules
• radioisotopes
• renal tubular transport
• tracers