126
Views
104
CrossRef citations to date
0
Altmetric
Original Article

Muscle Metabolites during Submaximal and Maximal Exercise in Man

, &
Pages 385-394 | Received 01 Jul 1970, Accepted 05 Oct 1970, Published online: 08 Jul 2009
 

Abstract

Methods are described for the determination of ATP, CP, Pi, glycogen, G-6-P, and lactate concentrations in muscle specimens (15 mg) obtained with a needle biopsy technique. Muscle biopsy specimens were obtained in two materials (n = 13; maximal oxygen uptake (max V˙o2) 61 ml × min−3 × kg−1 and n = 15; average max V˙o2 48 ml × min−1 × kg−1), at submaxi mal (55–95 per cent of max V˙o2). and at short time exhaustive work levels. A depletion of the ATP and CP stores in relation to the relative work load was observed while the muscle lactate concentration increased faster at higher work loads concomitant with a tendency to an increased glycolysis. The ATP and CP stores (the phosphagens) could maximally account for an alactacid anaerobic energy output equivalent to 1.2–1.3 liters of oxygen. The lactacid anaerobic energy output, however, seemed to start when the phosphagens were lowered to approximately 70% of the basic values which occurred during steady-state work at work loads in excess of 50% of maximal oxygen uptake.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.