Abstract
In healthy persons a fat meal followed by injection of heparin produced a marked decrease in the binding capacity of the thyroxine-binding proteins, as measured by the T3-test. Addition of fatty acids to plasma in vitro had similar effect on the T3-test. No effect was seen when heparin was given to fasting subjects or was added to plasma in vitro. The mechanism is thought to be a displacement of thyroid hormones from their carrier proteins.