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Original Article

Plasma and urine fibronectin concentration in kidney-transplanted patients

, , , , &
Pages 135-142 | Received 12 Jul 1983, Accepted 03 Oct 1983, Published online: 05 Aug 2009
 

Abstract

Plasma and urine fibronectin concentration was determined by electro-immunoassay and ELISA-method in patients who received renal transplantation. The plasma fibronectin concentration decreased both after the transplantation, in relation to the acute rejection of the graft, and in the relation to immunosuppressive therapy. Urine fibronectin excretion increased in relation to the kidney transplantation and acute rejection of the graft. In association with improved kidney function, the urine fibronectin excretion decreased. It is suggested that it might be of clinical importance to determine the excretion of fibronectin into the urine in patients undergoing kidney transplantation.

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