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Original Article

Galactose elimination kinetics in perfused rat liver after two thirds hepatectomy

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Pages 155-158 | Received 10 May 1983, Accepted 20 Oct 1983, Published online: 05 Aug 2009
 

Abstract

Galactose elimination kinetics was studied in isolated perfused livers (single pass) from rats subjected to two thirds partial hepatectomy 6 h earlier or immediately before investigation. No difference was found between the two groups in the maximum galactose elimination rate or in the half saturation galactose concentration. This is in contrast with in vivo observation of restored galactose elimination capacity 6 h after two thirds hepatectomy. The discrepancy indicates that extrahepatic factors may be of importance for the metabolic regulation in the liver during regeneration.

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