The Ca²⁺-standardization of Japan only may cause problems for the importation of foreign analyzers

Abstract

A serum based reference material for Ca²⁺ measurement has been established in Japan. cCa²⁺ in the reference material was assigned with a IFCC reference cell. Some improvements of the IFCC reference cell are described. A few non-Japanese Ca²⁺ analyzers have given very inaccurate results with the reference material. The Japanese authorities can therefore be expected to hamper their importation in the future. A world-wide external quality assessment scheme with the Japanese reference material is suggested to further identify and solve the problems.

Key Words:

• Directly cast membrane
• elimination of protein effect
• ETH1001/DOS membrane
• importation problems