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Abstract
Background and study aims. MRI-guided procedures combine high-quality imaging with lack of radiation. Percutaneous transhepatic cholangiodrainage under real-time MRI guidance (MRI-PTCD) seems promising, allowing targeted puncture and avoiding multiple blind passes and use of contrast, which are associated with standard PTCD's heaviest complications. Patients and methods. Aim of this study was to investigate the feasibility of MRI-PTCD in three outbred piglets. Obstructive cholestasis was induced by common bile duct ligation. Two days later, MRI-PTCD was performed (open MRI, 1.0 Tesla) with prototype MRI-compatible accessories. Visualization was achieved with a balanced steady-state free precession real-time sequence (bSSFP: 0.75 frames/s, TR/TE [ms]: 7.2/3.6; flip angle: 45°; 200 × 200 matrix size; resolution: 1.3 × 1.3 mm2, slice thickness: 7 mm). Cannulation of the bile ducts was followed by placement of Yamakawa drainages. Results. Twelve punctures were performed (four per animal, 10/12 successful); in 2/10 the bile ducts could not be cannulated. Animal survival was 100% and no significant complications occurred. Conclusions. Initial data show that MRI-PTCD can be successfully performed. This may lead to establishment of a new optimized PTCD technique compared to the standard approach under fluoroscopy.
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Acknowledgement
Project (10132816/10134231) financed by TSB Technologiestiftung Berlin (Zukunftsfonds Berlin). Co-financed by the European Union (European Fund for Regional Development).
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.