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Abstract
An increased sensitivity of different brain stem centers in patients with dumping symptoms following gastric resection, measured as emetic and carbon dioxide chemoreceptor sensitivity, has previously been demonstrated by the authors.
A method for determination of the standard threshold of the ventilatory response to carbon dioxide (sTCO2) was applied in 55 patients with peptic ulcer prior to gastric resection. The material comprised 21 males operated upon according to B II, 20 males according to B I, and 14 females according to B I. The patients were examined one year postoperatively for dumping complaints. An sTCO2 of 38.5 mm Hg was found to be a critical level. Cases with higher threshold values preoperatively did not get dumping symptoms of clinical significance. In 20 such cases there was only one exception. The severity of the dumping symptoms in the cases with a threshold value lower than 38.5 mm Hg, seemed to depend not only on the magnitude of the threshold value but also on the type of operation.