A Biochemical-cellular-morphological Explanation of the Development of Gastric Ulcer in Shay Rats

Abstract

Seven hours after pyloric ligation the acid-soluble organic phosphates increased both in the glandular and membranaceous stomach wall, whereas a pronounced decrease was found 24 hours after pyloric ligation in both parts of the stomach. The phospholipid phosphates were increased in the glandular and membranaceous parts of the stomach both at 7 and 24 hours after pyloric ligation. The deoxyribonucleic acid was less increased in the glandular than in the membranaceous stomach wall 24 hours after pyloric ligation, whereas the ribonucleic acid was only increased in the membranaceous stomach wall 7 and 24 hours after pyloric ligation.

Key-words:

• Biochemical phases of ulcer
• biochemistry
• gastric wall
• nucleic acids
• phosphate frations
• pyloric ligation
• stomach.