A Biochemical-cellular-morphological Explanation for Antiulcerogenic Effects of Parasympatholytics and of Surgical Vagotomy in Shay Rats

Abstract

The anti-ulcerogenic effects of parasympatholytics (atropine, Isopropamide, Gastrixone) and of bilateral surgical vagotomy were examined biochemically in Shay rats. According to our biochemical-cellular-morphological explanation, the parasympatholytics inhibit the first phase of development of Shay ulcer, while in the surgical vagotomy inhibits the second phase in ulcer development.

Key-words:

• Anti-ulcerogenic effects
• bilateral surgical vagotomy
• biochemical-cellular-morphological explanation
• biochemistry
• chemical structure of parasympatholytics and their biochemical effects
• nucleic acids
• parasympatholytics
• phosphate fractions
• Shay ulcer