Gastric Secretion of Iodide Related to Adrenocortical Activity. An Experimental Study in the Pylorus-Ligated Rat

Abstract

The effect of adrenalectomy and the administration of corticosteroids to adrenalectomized and sham-operated controls on the gastric secretion of iodide and hydrochloric acid were studied in a total of 210 albino rats during a 6-hour period after pyloric ligation. The volume, iodide content, and acidity of gastric contents were reduced significantly immediately after adrenalectomy. This effect was eliminated after 14 days. The iodide secretion was positively correlated to the volume of the gastric contents but not to their pH.

Key-words:

• Adrenal cortex hormones
• adrenalectomy
• gastric juice
• iodides